Is austerity responsible for the recent change in mortality trends beyond high-income nations? A protocol for an observational written report

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  1. http://orcid.org/0000-0001-6341-3521Gerry McCartneyi,
  2. Lynda Fentonane,2,
  3. Jon Minton1,
  4. Colin Fischbacheriii,
  5. Martin Taulbutane,
  6. Kirsty Little4,
  7. Ciaran Humphreysiv,
  8. Andrew Cumbers5,
  9. Frank Popham6,
  10. Robert McMaster5
  1. 1 Public Health Observatory, NHS Wellness Scotland, Glasgow, Scotland, United kingdom
  2. ii Public Health, NHS Greater Glasgow and Clyde, Glasgow, Scotland, United kingdom
  3. 3 Information Services Division, NHS National Services Scotland, Edinburgh, Scotland, United kingdom
  4. 4 Public Health Wales, Cardiff, Wales, Great britain
  5. v Adam Smith Business Schoolhouse, Academy of Glasgow, Glasgow, UK
  6. half-dozen CSO/MRC Social and Public Health Sciences Unit, Academy of Glasgow, Glasgow, Scotland, UK
  1. Correspondence to Dr Gerry McCartney; gmccartney{at}nhs.cyberspace

Abstract

Introduction Mortality rates in many high-income countries have changed from their long-term trends since around 2011. This paper sets out a protocol for testing the extent to which economic austerity can explain the variance in recent mortality trends across high-income countries.

Methods and analysis This is an ecological natural experiment study, which volition use regression adjustment to business relationship for differences in exposure, outcomes and confounding. All high-income countries with available information will be included in the sample. The timing of any changes in the trends for four measures of austerity (the Alesina-Ardagna Fiscal Index, existent per capita government expenditure, public social spending and the cyclically adjusted primary balance) will be identified and the cumulative departure in exposure to these measures thereafter will be calculated. These volition be regressed against the difference in the mean annual alter in life expectancy, mortality rates and lifespan variation compared with the previous trends, with an initial lag of ii years later the identified change point in the exposure measure. The role of underemployment and individual incomes as outcomes in their own right and as mediating any relationship between austerity and mortality will too be considered. Sensitivity analyses varying the lag period to 0 and 5 years, and adjusting for recession, will be undertaken.

Ideals and broadcasting All of the data used for this written report are publicly available, aggregated datasets with no individuals identifiable. In that location is, therefore, no requirement for ethical committee blessing for the report. The study will be lodged inside the National Health Service research governance system. All results of the written report will be published following sharing with partner agencies. No new datasets will be created equally office of this work for deposition or curation.

  • international health services
  • epidemiology
  • public health
  • statistics & research methods

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  • international health services
  • epidemiology
  • public wellness
  • statistics & inquiry methods

Strengths and limitations of this report

  • The available studies considering the touch of austerity on mortality trends either practise not consider the post-2014 menstruum or take weak designs.

  • Nosotros propose a theory-led and comprehensive approach to agreement the impact of austerity on recent bloodshed trends beyond high-income countries.

  • The hypotheses, data, populations and analyses are all specified in advance to avoid selective publication or post hoc rationalisation.

  • This arroyo uses ecological rather than individual-level data and is thus unable to appraise private exposure–issue relationships. In that location are also a express number of units of analysis (countries) available which restricts the number of measures that can be included in the modelling.

Background

Description of the trouble

The long-run improvement in all-crusade mortality rates across most loftier-income countries has recently changed such that the charge per unit of improvement has either slowed or reversed.1–seven Betwixt 2012 and 2016 (inclusive) for women, an average annual decrease in life expectancy occurred in Northern Ireland of ane.two weeks per twelvemonth; and the rate of increment (in weeks of life expectancy per year) slowed to 0.one in Iceland, ane.1 in England and Wales, 1.9 in the U.s.a., 2.v in Scotland and 2.7 in the netherlands, from 8 to 12 weeks per twelvemonth in the previous 5-year menstruum. Among men, the slowdown was even more than dramatic, from 10 to 17 weeks per twelvemonth between 2007 and 2011 to a reject of 1.seven and 0.4 in Republic of iceland and the USA respectively, and increases of but 4.0 in England and Wales, 4.5 in Scotland and 7.1 weeks per year in the netherlands.6 However, the change in life expectancy was non ubiquitous across all high-income countries, with continuing increases in Poland, Kingdom of denmark, Czech Republic, Switzerland, Korea and Japan.6There is as well prove that socioeconomic inequalities in health have increased in many countries over this time period.8 9

In the United kingdom of great britain and northern ireland, the recent slowdown in life expectancy improvement was accompanied by changes in mortality rates across about all age groups and causes of death.3 four The greatest contributions to the change in trend were the very substantial slowdown in the rate of improvement in cardiovascular mortality rates for those aged 55–85 years, a marked increase in drug-related deaths for those aged 35–54 years, and an increased mortality charge per unit from dementias for those aged over 90+ years.3 4 In the Us, the trends are driven past increased mortality rates amidst white not-Hispanics aged 25–64 years from 'deaths of despair' (drug-related deaths, alcohol-related deaths and suicides).ten

The substantial slowdown, or fifty-fifty reversal, in the rate of improvement in life expectancies across affected high-income countries is the most urgent and of import public health problem of our time.6 9 This paper sets out the protocol for the investigation of the office of austerity policies (ie, the pursuit of brusk-run government budget balance11 in explaining the inverse trend in mortality rates among loftier-income countries after 2008).

Hypothesis

In that location have been many hypotheses proposed to explain the recent changes in the mortality rate trends.12 The artefact and migration hypotheses have afterwards been shown to exist very unlikely explanations.vii The suggestions that this may be due to a natural limit to lifespan being reached is implausible given that: mortality rates accept changed beyond age groups and not just for the oldest; the trends are worst among the poorest groups who already accept lower life expectancy; and the countries with the highest life expectancy such as Japan have not experienced a changed trend. More plausible explanations include: cohort furnishings in the population from historical exposures13–fifteen; influenza, of which at that place were peculiarly astringent outbreaks in 2015 and 2018; obesity, which has increased across many high-income countries over the last 25 years and is understood to be associated with higher mortality rates16; increased social isolation17 and mental health problems,2 12 18 both of which may be mechanisms linking recession and thrift to bloodshed. A fuller discussion of the literature on these hypotheses is provided in online supplementary file ane.

Supplemental material

Recession and thrift

The financial crash of 2007–2008, the resulting 'neat recession', and the implementation of a variety of economic policy responses (including implementation of a fiscal stimulus in many countries up until effectually 2010, and subsequently 'austerity'19 preceded the current modify in mortality rate trends and have been suggested as the direct or indirect causes of the recent trends.i 8 20–22

Austerity is an ambiguous term, which has merely been practical in economic and policy soapbox since the 1950s.23 Thrift is associated with financial consolidation or retrenchment, that is, cuts in expenditure and/or increases in taxation. That said, some economists, such as Wren-Lewis,19 argue that austerity is a particular form of fiscal consolidation which leads to a 'noticeably larger output gap' that implies increases in involuntary unemployment and counteracts automatic stabilisers. Thus, for Wren-Lewis, fiscal consolidation needs not imply austerity, it becomes a question of degree and indeed timing. For example, fiscal consolidation during a period of sustained economic growth represents sound Keynesian need management in that it is countercyclical and not austerity in the sense used by Wren-Lewis. By contrast, financial consolidation applied during a downturn or recession is austerity in that it is likely to further debunk demand, although at that place are those who dissent from this statement (eg, Alesina and Perotti).24 Thus, for us, austerity refers to the suite of policies associated with discretionary fiscal consolidation that acts procyclically. Austerity may be employed for a number of reasons, including a belief that information technology reduces regime deficits, or is a machinery for correcting by conditions.23

As noted above, some aspects of public spending can increase, even when a government is otherwise committed to an austerity agenda, through the 'automatic stabilisers' within the economic system, such as increased spending on unemployment benefits due to an increase in the number of unemployment claimants. Indeed, reducing the spending on such 'automatic stabilisers' can be an objective of thrift policies. In the recent menstruum, near loftier-income countries pursuing austerity take focused on reducing public spending, rather than increases in taxes.25 Equally a outcome these United kingdom policies have tended to touch on nigh on lower income groups.26

The evidence on the impact of economical recession on health and mortality of populations, rather than individuals, is complex and not necessarily negative overall.27–29 There are several mechanisms through which economical downturns may affect health. Decreased household and individual incomes can limit the consumption of a range of goods and services that both support health and which can damage wellness (eg, alcohol).30 31 Increased unemployment (likewise equally underemployment and poor quality work) is well evidenced to exist causally related to increased mortality rates in the subsequent ten years.32

The regime response to recession is also important for health.29 In the Uk, there have been substantial existent-terms reductions in the value of many social security benefits (particularly for those of working age) and new restrictions on the eligibility and conditionality for receiving those benefits.two 18 33 In that location accept likewise been very substantial reductions in local government funding,34 with greater reductions in England than in Scotland or Wales.35 This impacts on a broad range of services, including educational activity, leisure, housing and some support services for those with item needs (eg, disabilities or substance misuse issues). A particular bear on on health has been proposed through the reduction in the budget available to provide social care services, something that is largely delivered to the elderly either living at home or in residential accommodation.33 36 It has been suggested that in the Uk this meant that fewer people could be fairly cared for outside the National Health Service (NHS), leading to lower quality care and increased demand on hospital services. Areas with the largest reductions in spending in England had the greatest mortality rate increases.22 33 37

Although there are a number of distinct hypotheses that may explain the recent trends, each of which may play a substantial, moderate, minimal or no causal function, it is important to recognise that several may collaborate as part of the aforementioned causal pathway and may exacerbate the bear on of each some other (effigy 1). Information technology is likewise possible that the impact of any unmarried gene may be dependent on the presence or absenteeism of another.38 Thus, if this study was to detect evidence for or against a function for austerity, this does not foreclose a role for other factors.

This study will test the hypothesis that the pursuit of austerity policies (measured in different means) impacted negatively on a range of mortality outcomes, and on household incomes and underemployment relative to populations that experienced a different policy approach.

Limitations of existing research

The difference betwixt exploratory research and causal research, and the risks of conflating the two, have been clearly described.39 A causal approach needs to avoid the risks that tin can ascend from multiple testing within a large dataset in the absence of a clear hypothesis, selective reporting of outcomes or subpopulations, picking item analytical approaches or baseline time periods without skillful justification which biases in favour of item outcomes, or publication bias towards findings that are more than interesting or which confirm pre-existing beliefs. At that place are likewise risks when different approaches to the data and analysis yield divergent results. For example, this can occur when the choice of using shorter or longer time periods to compare before and later a change in exposure, or where there are options for which comparison populations to use. There are too risks relating to how data are presented and the extent to which a modify in outcomes might be (de)contextualised from its pre-existing degree of variability.

At that place is a lack of clear preanalysis research protocols being published in this expanse to protect against selective publication or altered analysis approaches afterward initial work. The risks of this approach are reflected within the current literature examining the causes of the contempo slowdown in the improvement of mortality rates. Several studies have suggested that the 'great recession' (ie, the postal service-2008 economic downturn which occurred across many high-income countries following the financial crash) has been associated with negative health outcomes such equally suicide, mental health problems and mortality.40 However, many of these studies take been reliant on very unstable and short baseline periods,41–43 or accept been at risk of analysing but selected outcomes (eg, merely for men).44 The choice of the baseline period is also very of import in determining the magnitude of the recent change in trends, not least because of a flow of relatively fast improvement during the late 1990s and early on 2000s.2 45

Where decisions about which data to use, over what time series, with which comparisons and statistical approaches, tin can change the results (and implications for policy and practice), information technology is important to be clear on the rationale for those decisions to ensure that they adopt the virtually robust ways of addressing the research question and are at the lowest adventure of mistake, bias and confounding. Oftentimes, a lack of good data measuring relevant exposures and outcomes for the populations of involvement necessitate businesslike decisions on the methods adopted, but the extent to which pragmatism has driven research decision making is non ofttimes clear.

To avoid these bug in this expanse of research, and particularly considering of the politicised nature of the implications of findings in this expanse, we feel that it is important to publish a protocol for this programme of work prior to the analysis commencing. This is in line with recent recommendations for the conduct of observational research.46

Summary of what is known about the causes of the trouble

Several reviews take been published on the impact of austerity and recessions on bloodshed.2 27 29 40 47–55 In general, recessions are constitute to have negative health impacts for some specific outcomes, only not for overall mortality rates; austerity has negative impacts for both specific and overall outcomes. Although there are studies of the affect of historical periods of austerity, particularly in the UK context,56–58 we take identified only 4 studies specifically considering austerity (rather than recession) in the mail service-2010 period (tabular array 1). These do acquaintance greater austerity with relatively high mortality rates, although none employ information across 2014.

Table 1

Empirical literature relating overall thrift measures and wellness outcomes

Description of the theory that is to be tested

This written report will test the relationships laid out in effigy 2. Changing national incomes, the key indicator of recession, is both a causal factor in government public spending decisions and a result of government public spending decisions. For case, there has been substantial fence about whether the pursuit of austerity causes prolonged economical recessions.59 60 Withal, others have argued that reducing government debt, through austerity, is of import to increase economical growth.61 Including gross domestic production (Gross domestic product) as a means of adjusting for recessionary effects risks overadjustment of the austerity–wellness relationship considering of the potential for austerity to impact on Gross domestic product. To minimise this potential overadjustment, the length of economic downturn volition not be included as a variable. Instead, only the per centum change between the peak and trough in GDP per capita for the economical downturn which began around 2008 will be used as a means of adjusting for the scale of the initial recessionary result. Similarly, considering there are pathways betwixt the recession measure out and underemployment, and between austerity and underemployment, aligning for unemployment risks confusing the effects of austerity and recession. The arroyo to how these are to be handled is discussed further below.

The other factors in the theory are more than clearly linked in a causal direction in the short to medium run. Public spending (overall, on public service provision generally and on specific public services, and spending non on debt repayments), social security policy and personal taxation are all relevant policy decisions that grade the overall approach that tin be described as more or less orientated towards austerity. Nigh of these factors take both direct and indirect impacts on mortality outcomes, many through the important mediators of unemployment, wages and household incomes, simply too through the changes in the provision of item public services which could be expected to act differentially on particular population subgroups.25 The variation in the nature of austerity programmes (eg, those which might increment taxes on richer or poorer groups, or might cut spending on universal or targeted public services, or those which touch on on social security payments differentially by age) might be expected to take different impacts on mortality trends overall, and for specific population groups. However, this more detailed work is outwith the telescopic of this project, particularly considering of limitations in the availability of comparable data. We are also focused here on mortality outcomes as an easily measurable outcome, only that is not to downplay the importance of other measures of health.62

Methods

Austerity

This protocol is published in club to fulfil the best practise in observational epidemiological research as detailed in the Strengthening the Reporting of Observational Studies in Epidemiology statement.63 The data gathering, assay, interpretation and write-up for the written report will be undertaken between Oct 2019 and October 2020.

Aim

To measure out the contribution of thrift policies to the change in life expectancy and mortality rate trends later 2008 across high-income countries.

Hypotheses

The research questions, nil and alternative hypotheses to be tested in this work are detailed in tabular array 2.

Table ii

Research questions, null and alternative hypotheses

Design

As we cannot manipulate the exposure to thrift, an observational, ecological, 'natural experiment' study pattern will be adopted. Equally the exposure in this case across countries is a continuous rather than binary variable a family of regression models using the country as the unit of assay.64 More than specifically, a fixed-furnishings console model to reduce unmeasured (but relatively stable) confounding due to pre-existing differences betwixt countries (eg, welfare country type) volition be used.

Populations and settings

The sample frame for the study is the total populations of United nations-defined high-income countries, with subgroup analyses for men, women and specific age groups (<1 year, 1–14 years, 15–29 years, thirty–49 years, 50–69 years and 70+ years).

Exposures

The exposures of interest are listed in table 3, detailing the exposure for the main analysis and the exposures for the sensitivity analyses. Identification of the timing of the start of the austerity menstruation for each country volition be undertaken by plumbing fixtures a segmented regression model in R (using the 'segmented' parcel) to place the first turning betoken after 2007 using a time series from 1987 (to provide a minimum 20-year baseline menses) to the latest data point bachelor. This year will then become the signal from which the change in exposures and outcomes will be measured. An initial 2-twelvemonth lag betwixt the exposure and issue volition be used, and will be varied to 0 years (ie, simultaneous change) and to five years as sensitivity analyses. Those countries for which no turning point in the trend is identified for the catamenia subsequently 2007 will be allocated the median yr of austerity starting from those countries in which a change was detected.

Table iii

Information definitions and sources

For each of the austerity measures and the recession mensurate, the cumulative difference from the previous trend will be calculated and used as the exposure measure, equally indicated in effigy 3.

Outcomes

Each of the outcome measures detailed in table three will exist calculated from a start bespeak 2 years after the year in which a alter in exposure occurs (see the belittling arroyo below for the identification of that year) until the latest bachelor year. All of the outcome information will exist calculated every bit the mean annual change from the previous trends, to ensure comparability beyond countries which have differing availability of data later on the get-go of the exposure menstruum and to have into account the potential for differing rates of improvement prior to the recent flow. The percentage and accented mean annual alter in the outcomes volition exist calculated.

As means of approximating the mediation of whatsoever effects of underemployment and incomes the models will be adjusted for both variables. Finally, the models will be adjusted for real GDP per capita to ascertain the touch on of austerity afterward accounting for the economic downturn, although this will be interpreted cautiously, as thrift may take negative impacts on Gdp and thereby represent opposite causality in the relationship.

Patient and public involvement

Due to the secondary use of information and the absence of patient risks, no patients or members of the public were involved in the study.

Analytical approach

As the data are observational and reflect a 'natural experiment' with continuous exposure and issue variables, a family of stock-still-effects regression models volition be used to judge the human relationship betwixt the exposures and outcomes.

The first pace of the analysis will be a unproblematic descriptive characterisation of the trends in austerity, recession and outcome measures across nations. This will involve simple graphing of the trends over fourth dimension and comparisons of these trends in exposures across countries to highlight those countries that experienced more or less austerity, the timing of such policies, and the length of the exposure; the extent and timing of recession across countries and trends in the outcome measures.

Before regression models are fitted, scatterplots of each of the exposures and outcome measures will be plotted to check for spurious or not-linear associations. Any modify in the trends after 2007 in the exposure measures volition and then be identified by fitting a segmented regression model, and this will provide the first year for the thrift period. The full list of regression models to be run, including the sensitivity analyses, are shown in tabular array 4. Poisson or negative binomial models will be fitted every bit appropriate. We volition additionally explore whether or not it is possible to examination for interactions between the exposure variables.

Table four

Regression models to be fitted

Ethics and broadcasting

All of the data used for this report are publicly available, aggregated datasets with no individuals identifiable. At that place is therefore no requirement for upstanding committee approval for the study. The study will be lodged inside the NHS Health Scotland research governance system (which, over the course of the study will exist confederate into the Public Health Scotland research governance arrangement as part of an organisational change).

All results of the study will be published. Our approach to this will be to share our preliminary results and interpretation with the mortality special interest group administered by the Scottish Public Health Network and sponsored past the Directors of Public Health in Scotland for comment; and then our final newspaper with colleagues across the other U.k. public health agencies for information. We will then upload the paper to a prepublication website and submit the paper to a periodical for peer review and publication. If no peer review periodical is identified that is willing to publish the paper, a final version will be published on www.scotpho.org.uk. The study is due to get-go in December 2019 and be completed by Dec 2020 with a paper submitted for publication by this appointment.

There will non exist any new datasets created as part of this work for deposition or curation.

Beyond this analysis, nosotros intend to pursue several other related enquiry questions and approaches, acknowledging the importance of triangulating insights from different methods, particularly where those methods do not share the same biases.65 This includes assay of the impact of austerity within the Uk using smaller populations as the unit of analysis, and further analyses at international level using alternative methods.64

References

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